Patient Case: IgA Nephropathy Stage

Here is a case of IgA Nephropathy Stage 3 (FSGS) who gets rid of hormones gradually and gets a better effects.


Bella, Female, 21-year-old, USA


Dropsy in eyes.
1. Bella appeared to have dropsy in eyes in June, 2007 and got examinations in local hospital. At that time, urine protein 3+, occult blood 2+, diagnosis as Chronic Nephritis. She was given anti-inflammation treatment, but there shows no response.
2. Bella transformed into another hospital in her country and tests showed urine protein 3+, occult blood 3+. Renal biopsy revealed Focal Segmental Glomerulosclerosis—stage 3. Given prednisone, GTW and cyclophosphamide for 16 months, she didn’t get better.
3. Bella was hospitalized in our hospital on 23th, April, 2010. At that time, tests showed serum albumin 33.7g/L, 24-hour uric albumen ration 1.36g, BUN and Scr are both within normal range.
4. She adopted Micro-Chinese Medicine Osmotherapy third times per day. Meantime, she took prednisone 40mg/d and cyclophosphamide 2g/d for one month.
5. Her 24-hour uric albumen ration became 0.58g when she left our hospital on 24th, May, 2010. Then she was suggested to stop cyclophosphamide and reduced the dosage of prednisone to 25mg.
6. She continued Micro-Chinese Medicine Osmotherapy at home for three months. When she got recheck in local hospital at 2th, September, 2010, she said the result as follows: Serum Albumin 33.6g/L, 24-hour uric albumen ration 0.04g. At that time, prednisone has reduced to o20mg.
Discussion
IgA Nephropathy refers to the deposits of IgA and C3 in mesangial area. The main composition of IgA in glomeruli is IgA1, which mainly comes from the effects of B cells from marrow and lymphatic system and Th2 cell, as well as dietary antigen. According to medical experts, the deposits of IgA connect with the imbalance between Th1 and Th2.
The ingredients of Micro-Chinese Medicine have ability in regulating immune system and correcting the imbalance between Th1 and Th2, which can decrease the accumulation of IgA in renal area.