IgA Nephropathy:I Feel Stomach Acid

Kidney damages caused by IgA Nephropathy have impact on stomach function, which may lead to stomach acid. 


Each people has two kidneys locating on either side of the spin, just below the rib cage. Each kidney is about the size of your fist. Your kidneys keep some things in your body that you need and get rid of other things that you don’t. Besides urination and waste elimination, your kidneys also release some hormones to keep other organs healthy. And some of hormones are used to support your stomach and intestines functioning well. These hormones are known as “gastrointestinal hormone”.

When IgA Nephropathy develops into a serious condition, your stomach and intestines may get involved and releasing excessive stomach acid.
The side effects of hormone drugs
Compared with kidney damages, stomach acid in IgA Nephropathy patients is commonly triggered by side effects of hormone drugs, such as thunder god vine, cyclophosphamide etc.

The hormone drugs usually are used to deal with the acute inflammation and alleviate hematuria and proteinuria. Many patients usually experience IgA Nephropathy relapse, after hormone therapy.  Thereby, they need take these medicine for long time, which leads to serious side effects. And one of them is impaired stomach and intestine, which leads to stomach acid.


How to deal with stomach acid?
Usually, you are not suggested to stop the intake of hormone drugs immediately. You can have a talk with Chinese medicine therapist and get an herbal formula according to your individual condition. Many Chinese herbal medicines are restorative to digestive organs by limiting stomach acid, revitalize stomach and intestines and protect gastric mucosa etc.
However, not each herbal medicine is good for everyone suffering from stomach acid. The herbs choice and dosage depends on your individual condition.

Pediatric IgA Nephropathy Relapse

Why pediatric IgA Nephropathy easily relapse? It connects with what treatment you choose for you children, how well your children’s immunity and children fails to take care themselves.

What treatments do you choose for your children?


Many parents choose hormone medications for their children. Hormone treatment can eliminate relative symptoms of pediatric IgA Nephropathy swiftly, but it needs strict rules in dosage. Many children are troubled with relapse again and again, because their parents fail to obey their doctor’s strict rules seriously. You can’t let your children reduce or stop drugs, when you find the disappear of proteinuria or hematuria in your children. Otherwise, you will take another risk in aggravating your children’s condition.
Another reason for relapse with hormone treatment is that hormone only focuses on eliminating corresponding symptoms of Pediatric IgA Nephropathy, which actually derives from the damage of glomerular filter membrane. Ask your doctor to make some therapies in repairing the filter function of glomeruli, your children may have a better remedy from relapse.

How well about your children’s immunity?


Pediatric IgA Nephropathy is a kind of immune deficiency, which damage your children’s immunity against infection and virus. This is another reason for frequent relapse. Even a slight infection, a cold, a wound can call back the onset. You should prevent your children from these factors. Meantime, take useful measures to improve your children’s immunity, such as exercise, proper diet and supplement vitamins.

Your children fail to take care of themselves.
Many children patients are too young to take care of themselves. Sometime, they lose their attention on the change of symptoms, such as the increase or reduction of urine protein, urine blood etc. Patients should remind them to tell their discomforts at first time. Meantime, keep an eye on their daily habits which may be the triggers of the relapse.
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Is IgA Nephropathy Difficult to Cure

It can take months or years to treat IgA Nephropathy, but many suffers only find that some of their chronic symptoms never totally go away. Why dose IgA Nephropathy is difficult to cure?


● Low immunity. IgA Nephropathy is a kind of special immune deficiency. Patients have a lower immunity than normal patients. They are so weak in preventing virus invasion that any ailment can be threatener for aggravation.

● Unexplained cause. The cause of IgA Nephropathy is not known yet by far. What has been found is only that the deposits of IgA immune complex in mesangial area cause renal disorder to occur. Nobody can explain clearly how IgA immune complex deposits here. Medical doctors fail to prevent IgA Nephropathy taking place. But now what we can do is to remit the renal disorder and stop its persistent deterioration.

● Unsuccessful treating method. In most countries, people with IgA Nephropathy take their doctor’s advice to use hormone medications. However, hormone only can remit your symptoms, such as blood or protein in urine, but it fails to improve your renal function. In fact, many patients and doctors know clearly about that, but they can find another useful treating method in their own counties.

● Relapse. IgA Nephropathy is characterized with easy relapse. It is can be triggered by any inducing agents, such as cold, fatigue, infection, inflammation, bleeding, long-term hormones and so on .

Even though IgA Nephropathy is so difficult to cure, it is possible to be cured on the condition that choosing a right treatment at the early stage. It is much more efficient to risk over-treating it at the early stage than to have to treat it more extensively later.www.igasite.com

Minimal Change Disease and IgA Nephropathy

Most patients with minimal change of IgA Nephropathy only presents Hematuria and has no obvious pathological change, therefore some of them just let it go and hope it can cure itself. In fact, timely treatment is very necessary, for minimal change can aggravate patient’s condition, even progress into eventual uremia with unsuccessful control 


Minimal Change refers to that glomeruli are normal under the light microscopy and only a few parts appear to have slight broadening of mesangial area, with or without mesangial cells' proliferation. It is the level I, according to Lee’s Classification of IgA Nephropathy. The higher the level is, the severer the pathological change is.

By far, it is impossible for IgA Nephropathy disappears spontaneously without any treatment. However, if patient’s condition can be controlled at the early stage and keep it stable in a long time, patients usually can live a normal life. If not, patient’s condition will continue to aggravate and appear to have cresent, glomerulosclerosis and renal tubular fibrosis (similar with necrosis, you can refer to Grades of IgA Nephropathy) etc.

In clinic, without timely treatment, mild disease will come along with Hematuria accompanied with proteinuria, hypertension and edema etc from the simplex blood in urine. Once these obvious symptoms appear, patients always step into Level IV or Level V, which makes recovery and treatment more complex and hopeless.

According to clinical practice, if patients accept treatment to repair damaged renal tissue, stop renal persistent injury and block renal fibrosis, patients can keep their condition stable in a long time and show a good prognosis. Otherwise, patients will have to experience continuous relapse of IgA Nephropathy, which even can be triggered with mild cold or infection. Frequent recurrence
deteriorates renal fibrosis and eventually become renal failure and uremia.

What Will Happen to Me, If I Am Pregnant With IgA Nephropathy

When you are pregnant with IgA Nephropathy, your body has to work more for you and your baby. This overwork will usually aggravate renal condition, which will likely induce pregnancy complications in return.


During pregnancy, women tend to excess fluid retention, which makes mothers to have high blood pressure and the accumulation of toxic byproducts in their blood. Fetus will grow adversely when it is affected with anomaly in level of blood pressure from mother. For the reason that high blood pressure will make fetus get insufficient blood by placenta.

What’s more, if hypertension of mother can be controlled well, other risks are on the way. For example preeclampsia, it can lead to premature birth and metal retardation, as well as renal hemorrhages in mother-to-be.

Pregnancy also brings other serious health risks for both mother and fetus associated with IgA Nephropathy. The risk factors are Hypertension, Premature Labor, Miscarriage, Renal Function Declining, Urinary Tract Infections and Acute Renal Failure and so on.

In addition, IgA Nephropathy, as a kind of renal disease, can affect whole system of human body, such as immune system, mineral levels, nervous system, blood circulation and even your heart or bone. As a result, any system mentioned above may undergo risks during pregnance.

If you are suffering IgA Nephropathy while you are planning to have a baby, it is very necessary for you to have a talk with Nephrologists who will help increase the possibilities to have a healthier fetus/

The Definition of IgA Kidney Disease/Berger's Disease

Pathologic Change. 
The levels of pathologic change of IgA Nephropathy are various. At the early stage, it shows mild pathologic change, which is described as “focal”. At that time, only a few glomeruli can be found mild mesangial broadened and segmental proliferation. At the middle stage of IgA Nephropathy, the pathologic change will become more obvious. Diffuse mesangial proliferation can be found and cresent is rare to see.


Clinical manifestation. 
In clinic, IgA Nephropathy mainly presents as microscopic or gross Hematuria and/ or accompanied with proteinuria. A part of patients may appear to have nephrotic syndrome. Normally, IgA Nephropathy progresses slowly and eventually it will develop into uremia.

Common Knowledge of IgA Nephropathy.
IgA Nephropathy, or Berger’s Disease, refers in particular to a group of chronic glomerular diseases, which has similar pathological characteristics. In clinic, about 40%~45% of patients manifest as gross or microscopic Hematuria. 35%~40% of patients can appear to have microscopic Hematuria accompanied by proteinuria. The rest patients usually present nephrotic syndrome and renal failure.

Generally speaking, man has a greater possibility to have IgA Nephropathy that woman. As the pathologic levels and the damaged levels of glomeruli are various, patients should keep a sharp eye on the frequency of Hematuria, severity of proteinuria, blood pressure and renal injury. And then choose a right treatment according your own condition.

IgA Nephropathy and Urine Odor

When urine persistently smells bad or has a foul, strong or unusual odor, it indicates underlying causes of IgA Nephropathy, such as bloody urine, infection, the discharge of toxins etc.


Different smells usually indicates various potential injuries for IgA Nephropathy suffers.

Urine always presents like fishy smelling. It may be an indicator telling your blood in urine. You’d better to check urine test and see if you are undergoing Hematuria. If the answer is yes, your glomerular basilar membrane is possibly being threatened. You might as well communicate with your doctors that whether the medications you are taking for IgA Nephropathy aims at repairing glomeruli or not. Generally speaking, once your glomeruli are repaired, blood rarely appears in your urine again.

Urine odor also can follow infections with a foul smell. For instance, urine tract or cystitis can trigger the unusual scent. In this situation, you need to talk with your doctors as soon as possible and take immediate actions, for infections easily can trigger or aggravate IgA Nephropathy.

Urine odor is not always annoying signals. If it smells strong, namely, you urine has a strong ammonia quality, it may reveals that your some toxins, such as excess immune complex, are sent out through urine. Usually this happens in Chinese Medicine therapy. Many Chinese therapies have functions of degrading extracellular matrix which will removed out in urination.

In addition, odor urine also appears temporarily after eating certain food or taking certain medications. You should not worry too much about that.